Lumber core plywood is usually made with three plies, with two thin veneers on each side and a thick core. The outer veneers are typically made of a hardwood, while the inner core consists of strips of wood glued into one solid slab.
The inner core helps grasp screws, which makes it a good choice for projects that need a strong screw hold. One disadvantage is that poorly-made lumber core plywood may have voids within the core that diminish its strength and screw holding abilities.